Ismailia is the venue for two of the finest teams in the competition so far, Ghana and Uruguay to go head-to head for a place at the section's summit at stake.
Ghana-Uruguay, Ismailia, Friday 2 October, 21:30 (local time)
It is not just the pride of being at the head of Group D which is important to both Ghana and Uruguay going into this encounter, but the chance to remain in the familiar surroundings of Ismailia and avoid a clash with the team who tops Group E, which is also up for grabs. Ghana, fresh from their 4-0 demolition of England have a full-strength squad, but Uruguay are without the services of Diego Rodriguez and master-creator Jonathan Urretaviscaya who are serving one-match suspensions.
4 - The only previous meetings between these two nations took place in the final phases of FIFA competitions, twice at the FIFA U-20 World Cup and twice at the FIFA U-17 World Cup. Ghana have history on their side with two wins to one, the other match being a draw. The only South American victory came in the semi-finals of the FIFA World Youth Championship 1997, which ended 3-2 to La Celeste after extra time.
"For us, the third match is as important as the first. We'll be making a step up in terms of our opponents when we meet Uruguay, so we have to rise to the challenge. We need to keep our focus and keep pushing. We have a lot of work still to do," Sellas Tetteh, Ghana coach.
"We're not favourites against Ghana, but we're hoping to win the game in order to top the group. They're an excellent side and have shown their strengths in their opening two games and we'll have to be at our best to collect the three points," Diego Aguirre, Uruguay coach.